• Reducing Failure Rates of Phase 3 Clinical Trials: how microsimulation modelling can assist

    Of the three main phases of clinical trials, by far the most expensive part of the process is the Phase 3 trial, typically requiring from several hundred to several thousand participants and costing up to $20 million on average. Furthermore, the process is fraught with risks with up to 70% of Phase 2 trials and […]

  • Liver disease: unravelling the interacting risk factors

    Obesity is increasing across Europe and, together with alcohol consumption, is contributing to rising rates of chronic liver diseases, and related conditions [1,2,3]; alcoholic liver disease will shortly overtake ischaemic heart disease in the number of years of working life lost (3). Quantifying the epidemiological and economic burden of obesity and alcohol-related conditions is essential […]

  • NEWS: Making Conversations Count for All – Benefits of improving delivery of smoking cessation interventions for different socioeconomic groups

    Today, Cancer Research UK has published a new report ‘Making Conversations Count for All: Benefits of improving delivery of smoking cessation interventions for different socioeconomic groups’ which includes modelling conducted by HealthLumen. This builds on the previous 2020 report, which aimed to estimate the burden of active smoking related disease in the UK and quantify the health and economic […]

  • The future burden of chronic kidney disease (CKD): how we have climbed “INSIDE CKD” with AstraZeneca using microsimulation-based computer modelling to help improve health outcomes

    HealthLumen, in conjunction with AstraZeneca, have recently published a body of research from the “INSIDE CKD” programme, part of a major strategic initiative at AstraZeneca which is dedicated to changing the future for CKD patients. Our role is to support evidence-based policy making in CKD, which we do by harnessing the predictive power of microsimulation, […]

  • How leaving the car at home might improve health

    An analysis of the effect of lockdown on air pollution-related health in two London boroughs People around the world have spent parts of 2020 in lockdown. The Covid-19 pandemic has caused thousands of tragic deaths and damaged many people’s health directly and indirectly, but new research has shed light on a much-needed positive health development […]

  • Intern Series (4)

    We’re pleased to share the latest in our series of posts from our interns. Daniel Ohrenstein has just completed an extended 5-month stay with us working on some exciting new techniques for multiple risk factor modelling. Daniel Ohrenstein I recently completed an MSc in Machine Learning and Data Science at UCL, having graduated with a […]

  • Why we must work toward a recognised international standard in evaluation of upstream interventions

    New blog published this week by Evidence & Policy co-authored by our COO and Co-Founder Laura Webber. The blog builds off research by Laura and collaborators at Lancaster University and the University of York on the health impacts universal basic income (UBI) could have. The role of UBI has come to the fore during the […]

  • NEWS: Making Conversations Count – The health and economic benefits of improving smoking cessation support in the UK

    Today, Cancer Research UK has published a new report Making Conversations Work: The health and economic benefits of improving smoking cessation support in UK general practice which includes modelling conducted by HealthLumen. The report found that by 2039 improved delivery of stop smoking support in general practice in the UK could prevent: > 400,000 cases of smoking-related […]

  • 2020 Summer Intern Series (3)

    As we move into the autumn, we’re pleased to share the last in our series of posts from some of our first summer interns. Annie Estlin I recently graduated from the University of Cambridge with an MPhil in Epidemiology. It’s been incredibly exciting to work for HealthLumen this summer and apply my learning in the […]

  • 2020 Summer Intern Series (2)

    In the next installment of our summer intern series, we hear about the “day in the life” of one of our interns.    Yousef El-Tawil Hello! I am a medical student by background at Kings College London and I am currently completing my intercalated MSc in Global Health Policy at the London School of Economics. […]